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1.
China Journal of Chinese Materia Medica ; (24): 1415-1420, 2022.
Artigo em Chinês | WPRIM | ID: wpr-928068

RESUMO

This study mainly introduced the research on Chinese medicine toxicology funded by the National Natural Science Foundation of China(NSFC) in 2012-2021 and analyzed the research content. Furthermore, key research topics and characteristic research projects were discussed, such as the toxicity mechanism, relationship between toxicity and efficacy, toxicity-alleviating mechanisms, and new technology and methods. The review suggested that researchers should gain an in-depth understanding of the "toxicity" of Chinese me-dicine, turned to characteristic research topics, and build a toxicological research paradigm suited to the characteristics of Chinese medicine in project application.


Assuntos
China , Fundações , Medicina Tradicional Chinesa , Disciplinas das Ciências Naturais
2.
China Journal of Chinese Materia Medica ; (24): 253-258, 2022.
Artigo em Chinês | WPRIM | ID: wpr-927931

RESUMO

Through a retrospective analysis of the projects supported by the National Natural Science Foundation of China in the past ten years in the field of Chinese medicine for the treatment of malignant tumors, this article systematically summarized the main research contents and hotspots of Chinese medicine in efficacy enhancement and toxicity reduction. The efficacy enhancement of Chinese medicine mainly included the mitigation of molecule-targeted drug resistance, multidrug resistance, and chemotherapy resistance, synergistic efficacy enhancement, and radiotherapy sensitization. The toxicity reduction is mainly reflected in the alleviation of the side effects of radiotherapy and chemotherapy. In addition, Chinese medicine has advantages in reducing serious adverse reactions of malignant tumors, providing more options for the adjuvant treatment of tumors.


Assuntos
Humanos , China , Fundações , Medicina Tradicional Chinesa , Disciplinas das Ciências Naturais , Neoplasias/tratamento farmacológico , Estudos Retrospectivos
3.
China Journal of Chinese Materia Medica ; (24): 1010-1016, 2021.
Artigo em Chinês | WPRIM | ID: wpr-878966

RESUMO

The pharmacokinetics of traditional Chinese medicine is a subject that studies the dynamic changes of the absorption, distribution, metabolism and excretion of complex components of traditional Chinese medicine, which is an important method for elucidating the pharmacodynamic material basis, action characteristics, and compatibility mechanisms of traditional Chinese medicine. However, given on the fact that traditional Chinese medicine is a multi-dimensional and complex system with multiple components, multiple pathways, multiple targets, and an unclear pharmacodynamic material basis, the research on the pharmacokinetics of traditio-nal Chinese medicine has become a scientific and technological problem. Although the pharmacokinetics of traditional Chinese medicine has achieved remarkable development with the emergence of new theories, methods and technologies, there are still some problems in the application of the research direction of the pharmacokinetics of traditional Chinese medicine judging from the current application of the National Natural Science Foundation of China. Therefore, this article discussed the current research status on pharmacokinetics of traditional Chinese medicines by analyzing the projects funded by the National Natural Science Foundation of China in the past 5 years from 2016 to 2020, mainly including the application and funding analysis, main research contents of the projects in pharmacokinetics of traditional Chinese medicines. And the research hotspots, difficulties and deficiencies were focused in order to provide certain reference for researchers engaged in pharmacokinetics of traditional Chinese medicine.


Assuntos
China , Administração Financeira , Fundações , Medicina Tradicional Chinesa , Disciplinas das Ciências Naturais
4.
China Journal of Chinese Materia Medica ; (24): 3233-3237, 2020.
Artigo em Chinês | WPRIM | ID: wpr-828453

RESUMO

This paper introduces the application and financing of programs of efficacy material base of traditional Chinese medicine funded by the National Natural Science Foundation of China(NSFC), the Youth Science Fund and the Regional Science Fund from 2016 to 2019, and conducts analysis and summary in terms of research objects and analysis methods, with the aim to provide reference for applicants for programs of efficacy material base of traditional Chinese medicine.


Assuntos
China , Administração Financeira , Fundações , Medicina Tradicional Chinesa , Disciplinas das Ciências Naturais
5.
China Journal of Chinese Materia Medica ; (24): 2886-2892, 2019.
Artigo em Chinês | WPRIM | ID: wpr-773244

RESUMO

Through summarizing the applications and funding for research related to ethnomedicine and ethnopharmacology in the department of Health Sciences of the National Natural Science Foundation of China( NSFC) from 1986 to 2018,and analyzing the categories,numbers,funds and research contents of all funded projects including Mongolian,Uygur,Tibetan,Zhuang,Miao,the study is aimed to provide certain reference for the declaration of ethnic medicine project. The results showed that the national medicine project application numbers and the amount of funding growth after 2011 have increased significantly,but the overall level of research remained to be further promoted,and the lack of suitable for the study of ethnic medicine features and ways,has yet to mainland medical universities and research institutions to give more attention and jointly promote the development of basic research in the field of ethnic medicine.


Assuntos
China , Etnofarmacologia , Administração Financeira , Fundações , Medicina Tradicional
6.
China Journal of Chinese Materia Medica ; (24): 1991-1995, 2017.
Artigo em Chinês | WPRIM | ID: wpr-256063

RESUMO

In this paper, the funding situation of traditional Chinese medicine oncology research projects supported by National Natural Science Fund from 1986-2016 was reviewed. The characteristics of funded projects were summarized from funding amount, funding expenses, funding category, and the main research contents of projects, etc. At the same time, the main problems in the projects were analyzed in this paper, in order to provide reference for the relevant fund applicants.

7.
China Journal of Chinese Materia Medica ; (24): 3696-3701, 2016.
Artigo em Chinês | WPRIM | ID: wpr-307099

RESUMO

The paper reviewed the sponsorship and final reports of projects focus on Science of Chinese materia medica resource in Medical Science Department, National Natural Science Foundation of China. The applicant and supportive organizations were analyzed. The progress and results of some projects were summarized by research fields including formation mechanism of Dao-di herbs, research of plant taxonomy, breeding and cultivation of medical plants, ecological and environmental adaptability of Chinese materia medica resource, quality assessment of Chinese materia medica resource, and biosynthesis and regulation of active compounds. In addition, the potential problems and the most and least focused areas in the application were summarized for reference.

8.
China Journal of Chinese Materia Medica ; (24): 3379-3384, 2015.
Artigo em Chinês | WPRIM | ID: wpr-237702

RESUMO

The overall situation of projects of ethnomedicine and ethnopharmacology funded by the National Natural Science Foundation of China (NSFC) since 2008 has been presented in this paper. The main source of characteristics and innovation of the funded projects were summarized, which may come from several aspects, such as the ethnomedical theories, the dominant diseases of ethnomedicine, special diseases in ethnic minorities inhabited areas, unique ethnomedical therapy, special methods for applying medication, endemic medicinal materials in ethnic minorities inhabited areas, same medicinal materials with different applications. Examples have been provided to give references to the applicants in the fields of ethnomedicine and ethnopharmacology.


Assuntos
Humanos , Pesquisa Biomédica , Economia , China , Etnofarmacologia , Economia , Padrões de Referência , Administração Financeira , Medicina Tradicional , Economia , Padrões de Referência , Disciplinas das Ciências Naturais , Economia
9.
China Journal of Chinese Materia Medica ; (24): 10-13, 2014.
Artigo em Chinês | WPRIM | ID: wpr-319663

RESUMO

Projects which supported by National Natural Science Foundation of China (NSFC) in discipline of pharmacology of Chinese medicine between 2010 to 2013 financial years were reviewed. Based on these research items, new features and problems were summarized in this field.


Assuntos
Humanos , China , Fundações , Economia , Medicina Tradicional Chinesa , Economia , Disciplinas das Ciências Naturais , Economia , Pesquisa , Economia
10.
China Journal of Chinese Materia Medica ; (24): 6-9, 2013.
Artigo em Chinês | WPRIM | ID: wpr-346882

RESUMO

The applications accepted and approved by general program, young scientist fund and fund for less developed region of national natural science funds in the discipline of Chinese materia medica, NSFC in 2012 have been introduced. The research contents of the funded projects in the popular research areas have been summarized and the problems in the applications have been analyzed to give a reference to the scientists in the field of Chinese materia medica.


Assuntos
Humanos , China , Organização do Financiamento , Pessoal de Laboratório , Economia , Materia Medica , Química , Medicina Tradicional Chinesa , Economia , Disciplinas das Ciências Naturais , Economia , Recursos Humanos
11.
Chinese Journal of Integrated Traditional and Western Medicine ; (12): 1557-1560, 2013.
Artigo em Chinês | WPRIM | ID: wpr-231646

RESUMO

In recent years, projects funded by the Division V III of Health Sciences of the National Natural Science Foundation of China (NSFC) increased steadily, which enhanced the process of modernization of Chinese medicine (CM). We analyzed CM projects funded by NSFC during 2003 -2012, which aimed to provide reference to experts in the CM field.


Assuntos
China , Fundações , Medicina Tradicional Chinesa
12.
China Journal of Chinese Materia Medica ; (24): 4-6, 2004.
Artigo em Chinês | WPRIM | ID: wpr-276681

RESUMO

In this article, the items from 1999 to 2003 of pharmaceutics of Chinese medicine accepted and supported by subject of traditional Chinese medicine, No.9 department of life science, national natural science foundation of China (NSFC) have been reported, in several aspects, such as extracting process, preparation, biopharmaceutics, pharmacokinetic, etc. The problems in these items have also been analyzed briefly.


Assuntos
Biofarmácia , China , Formas de Dosagem , Medicamentos de Ervas Chinesas , Farmacocinética , Pesquisa , Apoio à Pesquisa como Assunto , Tecnologia Farmacêutica
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